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Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing in Chinese patients

Frontiers of Medicine   Pages 889-906 doi: 10.1007/s11684-023-0994-x

Abstract: Copy loss occurred in all samples, while gains were detected in 77.9% of the samples.The high level of copy number variations was significantly associated with poor progression-free survival

Keywords： primary central nervous system lymphoma     whole-genome sequencing     TMSB4X     copy number variation    

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Temperature variation of concrete box girder bridge

Jian WANG, Zhi FANG,

Frontiers of Structural and Civil Engineering 2009, Volume 3, Issue 4,   Pages 407-413 doi: 10.1007/s11709-009-0053-y

Abstract: On the basis of theoretical analysis and measurement on site, the temperature gradients and its variation

Keywords： temperature     transfer     correlation     radiation     variation    

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Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 421-427 doi: 10.1007/s11684-012-0223-5

Abstract:

In order to assess the value of liver volumetry in cirrhosis and acute liver failure (ALF) patients, we explored the correlation between hepatic volume and severity of the hepatic diseases. The clinical data of 48 cirrhosis patients with 60 normal controls and 39 ALF patients were collected. Computed tomography-derived liver volume (CTLV) and body surface area (BSA) of normal controls were calculated to get a regression formula for standard liver volume (SLV) and BSA. Then CTLV and SLV of all patients were calculated and grouped by Child-Turcotte-Pugh classification for cirrhosis patients and assigned according to prognosis of ALF patients for further comparison. It turned out that the mean liver volume of the control group was 1 058±337 cm3. SLV was correlated with BSA according to the regression formula. The hepatic volume of cirrhosis patients in Child A, B level was not reduced, but in Child C level it was significantly reduced with the lowest liver volume index (CTLV/SLV). Likewise, in the death group of ALF patients, the volume index was significantly lower than that of the survival group. Based on volumetric study, we proposed an ROC (receiver operating characteristic) analysis to predict the prognosis of ALF patients that CTLV/SLV<83.9% indicates a poor prognosis. In conclusion, the CTLV/SLV ratio, which reflects liver volume variations, correlates well with the liver function and progression of cirrhosis and ALF. It is also a very useful marker for predicting the prognosis of ALF.

Keywords： liver volume variation     cirrhosis     acute liver failure (ALF)    

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arsenic trioxide on proliferation and apoptosis of U266 cells and its relationship with the expression variation

ZHAN Rong, YU Qinghong, HUANG Haobo

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 356-360 doi: 10.1007/s11684-008-0068-0

Abstract: the proliferation and apoptosis of myeloma cell line U266 and its relationship with the expression variation

Keywords： VEGF expression     expression variation     culture supernatant     labeling     concentration    

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Estimating the number of Chinese cancer patients eligible for and benefit from immune checkpoint inhibitors

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 773-783 doi: 10.1007/s11684-021-0902-1

Abstract: The total number of cancer patients who are eligible for and will benefit from immune checkpoint inhibitorsThis cross-sectional study was conducted to estimate the number of Chinese cancer patients with eligibilityThe estimated number of eligible patients annually was 1 290 156 (55.18%), which included 888 738 malesThe estimated number of responders annually was 448 972 (19.20%), which included 309 023 males (20.88%hepatocellular carcinoma (n=277 100, 11.85%) were the top three cancer types with the highest number

Keywords： benefit     China     eligibility     immune checkpoint inhibitor     public health    

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Temporal variation of heavy metal pollution in urban stormwater runoff

Wen LI, Zhenyao SHEN, Tian TIAN, Ruimin LIU, Jiali QIU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5,   Pages 692-700 doi: 10.1007/s11783-012-0444-5

Abstract: surface) had significant effects on the strengths of the first flush effects, accounting for 72.9% of the variation

Keywords： urban stormwater     heavy metal pollution     temporal variation     event mean concentration     first flush effect    

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RESPONSE OF WHEAT COMPOSITE CROSS POPULATIONS TO DISEASE AND CLIMATE VARIATION OVER 13 GENERATIONS

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 3,   Pages 400-415 doi: 10.15302/J-FASE-2021394

Abstract:

Since the F5 (2005), three winter wheat composite cross populations (CCPs) based on germplasm specifically suitable for low-input conditions were subjected to natural selection under organic and conventional management. In the F6, each CCP was divided into two parallel populations (12 CCPs in total) and maintained continuously until 2018. Commonly used modern cultivars with different disease susceptibilities were grown alongside to assess the agronomic performance of the CCPs. The organically managed CCPs were comparable in yield and foliar disease resistance to two continuously used reference cultivars, Achat and Capo. In contrast, under conventional management the cv. Capo outyielded the CCPs (Achat was not tested), highlighting the importance of parental cultivar choice for specific management systems. The CCPs were found to be moderately resistant to brown rust and even to the newly emerged stripe rust races prevalent in Europe since 2011. Differences between the CCPs were mainly due to parental genetic background and were significant in the first five generations, but were no longer so in the last five generations. In addition, these differences tended to vary depending on the experimental year and the environmental stresses present. In conclusion, the CCPs despite being derived from older cultivars are able to compete with more recently released reference cultivars under organic farming practices and represent a dynamic germplasm resource.

 

Keywords： evolutionary breeding     heterogeneous crop population     management system    

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Identification of structural parameters and boundary conditions using a minimum number of measurement

Ali KARIMPOUR, Salam RAHMATALLA

Frontiers of Structural and Civil Engineering 2020, Volume 14, Issue 6,   Pages 1331-1348 doi: 10.1007/s11709-020-0686-4

Abstract: This article proposes a novel methodology that uses mathematical and numerical models of a structure to build a data set and determine crucial nodes that possess the highest sensitivity. Regression surfaces between the structural parameters and structural output features, represented by the natural frequencies of the structure and local transmissibility, are built using the numerical data set. A description of a possible experimental application is provided, where sensors are mounted at crucial nodes, and the natural frequencies and local transmissibility at each natural frequency are determined from the power spectral density and the power spectral density ratios of the sensor responses, respectively. An inverse iterative process is then applied to identify the structural parameters by matching the experimental features with the available parameters in the myriad numerical data set. Three examples are presented to demonstrate the feasibility and efficacy of the proposed methodology. The results reveal that the method was able to accurately identify the boundary coefficients and physical parameters of the Euler-Bernoulli beam as well as a highway bridge model with elastic foundations using only two measurement points. It is expected that the proposed method will have practical applications in the identification and analysis of restored structural systems with unknown parameters and boundary coefficients.

Keywords： structural model validation     eigenvalue problem     response surface     inverse problems    

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Erratum to: Meter-scale variation within a single transect demands attention to taxon accumulation curves

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 6, doi: 10.1007/s11783-022-1560-5

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Short-term effect of temperature variation on the competition between PAOs and GAOs during acclimation

Nanqi REN, Han KANG, Xiuheng WANG, Nan LI

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 2,   Pages 277-282 doi: 10.1007/s11783-010-0226-x

Abstract: During the 34 days operation, SBR was set with temperature variation(0–5 d, 22±1°C; 6–13 d, 29±1°C; 14Under sudden and substantially temperature variation, from 22±1°C to 29±1°C and then to 14±1°C, the domination

Keywords： fluorescent in situ hybridization (FISH)     tetrad forming organisms (TFOs)     temperature variation     enhanced    

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Multi-stage dual replica bit-line delay technique for process-variation-robust timing of lowvoltageSRAMsense

Shou-biao TAN,Wen-juan LU,Chun-yu PENG,Zheng-ping LI,You-wu TAO,Jun-ning CHEN

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 8,   Pages 700-706 doi: 10.1631/FITEE.1400439

Abstract: technique is proposed for reducing access time by suppressing the sense-amplifier enable (SAE) timing variationCompared with the traditional technique, this strategy, using statistical theory, reduces the timing variation

Keywords： Process-variation-robust     Sense amplifier (SA)     Replica bit-line (RBL) delay     Timing variation    

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SPATIOTEMPORAL VARIATION OF WATER QUALITY AND ALGAL BIOMASS IN ERHAI LAKE AND ITS ENVIRONMENTAL MANAGEMENT

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 4,   Pages 566-578 doi: 10.15302/J-FASE-2023520

Abstract:

Elucidating the spatiotemporal pattern of water quality and algal biomass is crucial for accurately tracing pollution sources and reducing the risk of algal blooms in lake systems. This study analyzed the spatiotemporal variability of water quality and algal biomass in Erhai Lake from 1994 to 2021 using water quality index (WQI), Mann-Kendall test and Sen’s slope combined methods. The potential causes of water quality deterioration and algal biomass dynamics were also elucidated. The results showed that the historical changes in the water environment of Erhai Lake mainly had three stages: satisfactory (1994‒2001), deteriorating (2002‒2010) and improving (2011‒2021). The changes in water quality and algal biomass were primarily affected by total nitrogen, total phosphorus and chemical oxygen demand in different stages. The water environment of Erhai Lake is currently improving significantly, starting in the southern area that is furthest from the sources of agricultural pollution, especially in summer and autumn. This is attributed to the implementation of control measures resulting in lower pollutant loads at particular times and places. Therefore, it is necessary to continue to promote standardized livestock farming, to strengthen rural wastewater collection and to investigate measures such as the interruption of the endogenous cycle.

Keywords： Erhai Lake     control measures     water environment     water quality index (WQI)    

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Seasonal variation of nitrogen and phosphorus in Xiaojiang River—A tributary of the Three Gorges Reservoir

Zhe LI , Jinsong GUO , Man LONG , Fang FANG , Jinping SHENG , Hong ZHOU ,

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 3,   Pages 334-340 doi: 10.1007/s11783-009-0039-y

Abstract: The variation of TN/TP ratio was caused by a variation in TN rather than in TP when TN/TP<22.When TN/TP ≥ 22, the variation of TP affected the TN/TP ratio more significantly than TN.

Keywords： Three Gorges Reservoir     eutrophication     nitrogen     phosphorus     seasonal variation     chlorophyll    

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Temporal variation of PM-associated health effects in Shijiazhuang, Hebei

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-020-1376-0

Abstract:

•Annual mean PM2.5 in Shijiazhuang were 87, 95, and 82 µg/m3 in 2015–2017.

Keywords： PM2.5     Health effects     Integrated exposure-response model     Shijiazhuang    

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Forecast method for used number of parts and components based on complex network

LIU Fu-yun, QI Guo-ning, YANG Qing-hai

Frontiers of Mechanical Engineering 2006, Volume 1, Issue 4,   Pages 479-484 doi: 10.1007/s11465-006-0064-5

Abstract: Applying directed complex network to model the main structure of a product family, according to in-degree bi-logarithmic coordinate distribution curve and distribution rule of nodes of the network, in-degree evolving rule of nodes of the network is presented and analytic expression of in-degree probability density of nodes is derived. Through the analysis of the relation between existing kinds of components and existing product numbers, an expression of the relation between kinds of components and product numbers is derived. A forecast method for the increment of component numbers and parts based on the increment of products is presented. As an example, the component numbers of an industrial steam turbine product family is forecasted, forecast result verified and forecast error analyzed.

Keywords： complex network     industrial     component     analytic expression     forecast    

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Title Author Date Type Operation

Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing in Chinese patients

Journal Article

Temperature variation of concrete box girder bridge

Jian WANG, Zhi FANG,

Journal Article

Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Journal Article

arsenic trioxide on proliferation and apoptosis of U266 cells and its relationship with the expression variation

ZHAN Rong, YU Qinghong, HUANG Haobo

Journal Article

Estimating the number of Chinese cancer patients eligible for and benefit from immune checkpoint inhibitors

Journal Article

Temporal variation of heavy metal pollution in urban stormwater runoff

Wen LI, Zhenyao SHEN, Tian TIAN, Ruimin LIU, Jiali QIU

Journal Article

RESPONSE OF WHEAT COMPOSITE CROSS POPULATIONS TO DISEASE AND CLIMATE VARIATION OVER 13 GENERATIONS

Journal Article

Identification of structural parameters and boundary conditions using a minimum number of measurement

Ali KARIMPOUR, Salam RAHMATALLA

Journal Article

Erratum to: Meter-scale variation within a single transect demands attention to taxon accumulation curves

Journal Article

Short-term effect of temperature variation on the competition between PAOs and GAOs during acclimation

Nanqi REN, Han KANG, Xiuheng WANG, Nan LI

Journal Article

Multi-stage dual replica bit-line delay technique for process-variation-robust timing of lowvoltageSRAMsense

Shou-biao TAN,Wen-juan LU,Chun-yu PENG,Zheng-ping LI,You-wu TAO,Jun-ning CHEN

Journal Article

SPATIOTEMPORAL VARIATION OF WATER QUALITY AND ALGAL BIOMASS IN ERHAI LAKE AND ITS ENVIRONMENTAL MANAGEMENT

Journal Article

Seasonal variation of nitrogen and phosphorus in Xiaojiang River—A tributary of the Three Gorges Reservoir

Zhe LI , Jinsong GUO , Man LONG , Fang FANG , Jinping SHENG , Hong ZHOU ,

Journal Article

Temporal variation of PM-associated health effects in Shijiazhuang, Hebei

Journal Article

Forecast method for used number of parts and components based on complex network

LIU Fu-yun, QI Guo-ning, YANG Qing-hai

Journal Article